Exosomes · Epigenetic · retinAL
MESOTHERAPY & Microneedling
Exosomes · Epigenetic · retinA
Advanced Skin Renewal Protocol by mesoestetic®
Modern aesthetic medicine has evolved beyond single-ingredient trends. True, long-term skin improvement requires a science-led, personalised and progressive approach that supports regeneration, renewal and optimal skin function.
At The Beauty Studio IOM, we offer Exosomes · Epigenetic · retinA, an advanced professional skin renewal protocol based on Skinretin Xpert by mesoestetic®. This treatment combines exosomes, epigenetic technology and retinA-based renewal, and is performed in combination with professional chemical peels, microneedling and transdermal delivery technologies, including electroporation (virtual mesotherapy), to maximise skin penetration and results.
What Are Exosomes in Skin Rejuvenation?
Exosomes are microscopic extracellular vesicles that act as cellular messengers, supporting communication between skin cells and promoting repair and regeneration.
In aesthetic practice, exosomes are used to:
- Support skin repair and recovery
- Improve overall skin quality
- Reduce inflammation
- Strengthen the skin barrier
Many clinics offer exosome-only treatments. While beneficial, these are often used as boosters. In our protocol, exosomes form part of a complete skin renewal system, not a standalone treatment.
A Complete Skin Renewal Protocol
Exosomes · Epigenetic · retinA is a global professional protocol built on four complementary pillars, designed to work synergistically for long-term skin health.
1️⃣ Exosomes – Regeneration & Skin Repair
We use plant-derived exosomes from Centella asiatica, selected for their high safety profile and regenerative properties.
They help to:
- Support skin regeneration
- Reduce inflammation
- Improve microcirculation
- Repair and strengthen the skin barrier
2️⃣ Epigenetic Technology – Optimising Skin Function
Epigenetic technology focuses on how skin cells function, helping to optimise cellular behaviour in response to ageing, stress and environmental factors.
Rather than altering genetics, this approach supports:
- Improved skin resilience
- Better response to professional treatments
- Long-term improvement in skin quality
3️⃣ retinA Technology – Advanced Skin Renewal
At the core of the protocol is retinA technology, combining advanced vitamin A derivatives:
- Retinol
- Retinal
- Hydroxypinacolone Retinoate
This combination stimulates collagen and elastin production, accelerates cell renewal and improves texture, tone and luminosity, while respecting skin tolerance.
4️⃣ Transdermal Delivery – Electroporation / Virtual Mesotherapy
To enhance the effectiveness of the active ingredients, our protocol incorporates transdermal delivery technology, also known as electroporation or virtual mesotherapy.
This technology temporarily increases skin permeability, allowing active ingredients to penetrate more efficiently into the skin without needles or injections.
Benefits of electroporation include:
- Enhanced penetration of exosomes and retinA actives
- Improved treatment efficacy
- Non-invasive and comfortable application
- Suitable for clients who prefer needle-free treatments
Retinol vs Retinal – Why retinA Matters
- Retinol works gradually and is ideal for maintenance and early signs of ageing.
- Retinal is more potent, requiring only one conversion step, delivering faster and more visible skin renewal.
By combining both within retinA technology, the skin benefits from controlled, progressive and effective renewal.
Treatment Protocol & Sessions
Exosomes · Epigenetic · retinA is delivered as a course of treatments, not as a single session.
Our protocol
- Treatments are performed every 15 days
- Sessions are combined with professional clinic protocols
- This schedule allows adequate skin recovery while maximising penetration and results
Personalised approach
The protocol is fully customised based on:
- Individual skin condition
- Skin tolerance and response
- Specific skin concerns and goals
The total number of sessions varies per client and is determined following a professional consultation and skin assessment.
Home care
A dedicated home-care routine is an essential part of the protocol to support results and long-term skin health.
Benefits of the Protocol
- Improves skin firmness and elasticity
- Enhances luminosity and evens skin tone
- Refines texture and smooths fine lines
- Strengthens the skin barrier
- Maximises penetration of active ingredients
- Supports long-term skin health
- Provides progressive and sustainable results
Mild redness, sensitivity or light flaking may occur as part of the retinisation process, which is normal and expected.
Skin Ageing – A Realistic Perspective
Skin ageing is a natural and continuous biological process. While it cannot be stopped, it can be managed and supported with advanced professional treatments, appropriate skincare and healthy habits.
Maintenance treatments may be recommended to prolong results.
Why mesoestetic®?
mesoestetic® is a globally recognised pharmaceutical company specialising in medical-grade aesthetic solutions, known for its commitment to research, innovation and structured clinical protocols.
The Skinretin Xpert range reflects this philosophy by focusing on long-term skin quality, not short-term cosmetic fixes.
Consultation & Suitability
A consultation and skin assessment with Ara are required prior to treatment to ensure suitability and to create a personalised treatment plan.
💷 Suggested Pricing (UK / Isle of Man)
Single Session
£180 – £220 per session
(depending on peel, microneedling and electroporation included)
Recommended Packages
Course of 4 sessions:
£680 – £760
Course of 6 sessions: ⭐ Most recommended
£960 – £1,080
