mesotherapy - micro injections
Scalp, Face and body
Mesotherapy injections are a non-invasive cosmetic procedure that is becoming increasingly popular due to their effectiveness in treating a wide range of skin conditions. Aesthetic mesotherapy involves injecting small amounts of vitamins, minerals, and other nutrients into the skin to reduce the appearance of fine lines, wrinkles, and other signs of aging. Skin mesotherapy, on the other hand, involves using similar injections to improve the overall health and appearance of the skin. Both treatments are performed by licensed professional and can be tailored to meet the specific needs of each patient. Mesotherapy injections are a safe and effective alternative to more invasive procedures, and patients can expect to see visible results after just a few sessions. If you're looking to improve the appearance of your skin without undergoing surgery, mesotherapy injections may be the perfect solution for you.
Indications
Aesthetic mesotherapy addresses skin rejuvenation, cellulite, sun damage, scar reduction and alopecia. There are various indications for mesotherapy, including pain management and aesthetic mesotherapy. For pain management there is a different field of mesotherapy, where this technique is used to relieve rheumatism, arthritis and muscle pain and sports injuries, amongst many other. Another uses include smoking cessation, allergy and ophthalmological pathology.
In the aesthetic field, the concern is primarily the effectiveness of the poly-revitalising solutions employed in mesotherapy and what happens in skin when those solutions are used.
To treat using mesotherapy, a solution containing small amounts of various substances such as vitamin C, vitamin A, vitamin E, vitamin B in nearly all its forms, amino acids, minerals (like calcium, phosphorous and magnesium), nucleosides, coenzymes, antioxidants, and hyaluronic acid is injected. This solution is injected into the epidermis and the dermis using three injection techniques. It is also possible to use micro needling or a meso-gun.
Both young skin and more aged skin can be targeted. In aged skin the treatment aids hydration, reduces the anti radical action and fights against the effective of oxidative stress. Radiance can also be achieved, improving the density, the tone of the skin, and its tonicity. The results of mesotherapy are progressive and accumulative and the advantage is that it is non-invasive and non-traumatic.
Ageing skin
Beautiful skin tends to be defined as smooth, even coloured and tone, radiant, firm and plump, with small pores, no wrinkles, no blemishes, no sagging, and no hyperpigmentation. Everyone desires luminescent, glowing, hydrated skin; a skin that is neither too dry, nor too oily, and would like to keep it this way forever. However, unfortunately the ageing process catches us all.
After the age of 30, it’s common to see that the eyebrows begin to descend. In our 40s, we may have excess eyelid skin, the glabella frown lines start to show and the nasal brow will fall also. By the 50s, forehead wrinkles start to show, the glabella becomes more pronounced and there is excess skin and vertical lines in the perioral region. When we arrive in our 60s, things get a bit worse. There are perioral and neck wrinkles, the nose begins to droop and the glabella becomes even more pronounced. By the age of 70 these developments become more visible as the skin thins even more. We also note a reduction in facial fat and a loss of volume. Muscular hyperactivity is a further reason of skin ageing.
Ageing factors
There are internal and external factors affecting ageing. Internal factors include genes, time, evolution and expression. When we look at external factors we find smoking, sun exposure, lifestyle, and pollution. For instance, those living in London are likely to age quicker than those in Cornwall.
So what happens to the skin? The epidermis thins, and the rate of cell renewal decreases. Photo ageing causes thinning of the epidermis with abnormal keratinocyte differentiation and dryness of the stratum corneum, which is due to the lack of hyaluronic acid.
When the junction between the dermis and epidermis thins, the ageing process becomes more pronounced in the dermis. A quantitative and a qualitative change occurs in collagen types I and III and changes to the fibroblasts – the extracellular matrix and collagen, the structural framework for human tissue.
The role of fibroblasts
Understanding the ageing process and the importance of fibroblasts is the key to understanding how mesotherapy works.
The fibroblasts are concerned primarily with maintenance and tissue metabolism and their correct functioning is responsible for structural and biochemical alterations, change in perception, permeability and capacity of scar formation. Fibroblasts make collagen, glycosaminoglycans, reticular and elastic fibres, glycoproteins found in the extracellular matrix, and cytokine TSLP. They also represent the major skin type in the dermis and are responsible for producing and maintaining the extracellular connective tissue, which gives the skin its youthful look.
However, as time passes, fibroblasts stop being able to keep the skin looking youthful. The exact reason why remains unclear, but what we do know that there is an important reason for this change in the dermis—perhaps an age related increase in oxidative stress, due to alteration in the balance between production and elimination of reactive oxygen.
Each of the components used in mesotherapy solutions such as NCTF HA has a physiological effect on the skin cells. The main principle is that ageing skin is supplied with various substrates that are key to the adequate functioning of the fibroblasts. These include vitamin, mineral element, amino acid, nucleotide, coenzyme and antioxidant as well as hyaluronic acid. Fibroblasts will work more efficiently if they are provided with the nurturing environment in which they can function properly, and the substrate substance looks after creating such an environment.
Putting all these multiple components together is not enough to guarantee the actual efficacy, as they need to maintain the stability and integrity in the formulation. It is very important to note that the formulation is sterilised by double filtration and not autoclaving, because those substrates are very sensitive to the heat.
composition of poly-reviling solutions used in mesotherapy:
- Poly-reviling solutions are typically composed of a mixture of vitamins, minerals, amino acids, and other nutrients that are beneficial for the skin.
- The exact composition of the solution can vary depending on the specific needs of the patient.
- Common ingredients found in poly-reviling solutions include vitamin C, vitamin E, hyaluronic acid, glutathione, and various B vitamins.
- These solutions are typically mixed with a local anesthetic to minimize any discomfort during the injection process.
- Poly-reviling solutions are designed to be injected directly into the skin, where they can be absorbed and utilized by the body.
- The goal of these injections is to improve skin health, reduce the appearance of fine lines and wrinkles, and promote a more youthful, radiant appearance.
- The use of poly-reviling solutions in mesotherapy is generally considered safe, but as with any medical procedure, there is a risk of side effects or complications. It is important to choose a qualified practitioner and to discuss any concerns with them before undergoing treatment.
Evidence
Preclinical and some clinical trials evidence is available to support the effectiveness of mesotherapy treatments, as well as long-term international experience in the clinical use of such preparations.
Studies of meso-needling show that the formation of new collagen and elastin after passing a needle has an increase of 206%.
Studies looking at a simulation of cell multiplications on young skin and on aged skin, show 147% for young and 148% on more aged skin. New collagen stimulation shows an increase of 166% intracellularly and 256% extracellularly, and protection against oxidative stress can increase up to 90%.
I have studied patients in Paris and London, who showed amazing results after just five sessions of mesotherapy—which is standard amount we recommend. The results varied in each individual case, but in general we can say that the quality of the skin improved overall, including reductions of crow’s feet as well as nasolabial fold, and an evident reduction of pigmentation. Applied on a regular basis, mesotherapy reduces sun damage, and we see this when we use such solutions for ageing hands, where loss of firmness and sunspots are clearly improved.
Possible side effects
Short-term side effects, such as mild pain, redness, swelling, and bruising are relatively common and an expected consequence of the injections themselves, but true complications are rare. Occasionally, small lumps, bruising, swelling and discomfort may also occur. Disinfecting the skin before the treatment is important to avoid possible infections.
Conclusion
The goal of the poly-revitalising solutions is to create a favourable micro-environment for more optimal fibroblast activity. These solutions help fibroblasts work effectively. Mesotherapy in the aesthetic field is one of the safest existing techniques if it is done accordingly.
Frequently asked questions and answers that patients might have about mesotherapy treatments:
- What is mesotherapy? Mesotherapy is a non-invasive cosmetic procedure that involves injecting small amounts of a customized solution into the skin to improve its overall health and appearance.
- What types of mesotherapy are available? There are several different types of mesotherapy, including aesthetic mesotherapy, which is used to reduce the appearance of fine lines and wrinkles, and skin mesotherapy, which is used to improve the overall health of the skin.
- How many sessions will I need? The number of sessions required will vary depending on the specific treatment and the individual patient. Your practitioner will work with you to develop a personalized treatment plan.
- Is mesotherapy painful? The injection process can cause some minimal discomfort.
- Are there any risks or side effects? As with any medical procedure, there is a risk of side effects or complications. However, mesotherapy is generally considered safe when performed by a qualified practitioner.
- How long does it take to see results? Results can vary depending on the specific treatment and the individual patient, but many patients report seeing noticeable results after just a few sessions.
- How can I prepare for my mesotherapy treatment? Your practitioner will provide you with specific instructions on how to prepare for your treatment, but in general, you should avoid taking blood-thinning medications, such as aspirin or ibuprofen, for a few days prior to your appointment.
- Is there any downtime after mesotherapy? Most patients are able to return to their normal activities immediately after treatment, although some may experience mild redness or swelling at the injection site for a short period of time.
- How long does each session last? The length of each session will vary depending on the specific treatment and the individual patient, but most sessions last between 30 minutes and an hour.
- Can mesotherapy be used on other parts of the body besides the face? Yes, mesotherapy can be used on other parts of the body, such as the neck, décolletage, hands, and scalp.
- Are there any restrictions on activities after mesotherapy? Your practitioner will provide you with specific instructions on what activities to avoid after treatment, but in general, you should avoid strenuous exercise and excessive sun exposure for a few days after the procedure.
- How much does mesotherapy cost? The cost of mesotherapy can vary depending on several factors, such as the location of the clinic, the qualifications and experience of the practitioner, and the specific type of mesotherapy solution used. It is recommended that you research prices in your area and consult with a qualified practitioner to determine the cost of your treatment.
- Is mesotherapy suitable for everyone? Mesotherapy is generally safe for most people, but it may not be suitable for individuals with certain medical conditions, such as blood clotting disorders or allergies to the ingredients used in the solution. Your practitioner will perform a thorough medical evaluation before recommending mesotherapy treatment.
- How long do the results of mesotherapy last? The length of time that results last will vary depending on the specific treatment and the individual patient, but many patients report seeing results for several months after treatment. Regular maintenance sessions may be required to maintain the results.
